2HJH: Crystal Structure Of The Sir2 Deacetylase

PDB ID: 2HJHDownload
MMDB ID: 63573
PDB Deposition Date: 2006/6/30
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 2HJH: dimeric; determined by author
Molecular Components in 2HJH
Label Count Molecule
Proteins (2 molecules)
2
Nad-dependent Histone Deacetylase Sir2
(Gene symbol: SIR2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
Zinc IonZinc Ion
2
2
(2r,3r,4s,5r)-5-({[(R)-{[(R)-{[(2r,3s,4r,5r)-5-(6-Amino-9h-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl]methoxy}(Hydroxy)phosphoryl]oxy}(Hydroxy)phosphoryl]oxy}methyl)-3,4-Dihydroxytetrahydrofuran-2-Yl Acetate(2r,3r,4s,5r)-5-({[(R)-{[(R)-{[(2r,3s,4r,5r)-5-(6-Amino-9h-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl]methoxy}(Hydroxy)phosphoryl]oxy}(Hydroxy)phosphoryl]oxy}methyl)-3,4-Dihydroxytetrahydrofuran-2-Yl Acetate
3
2
NicotinamideNicotinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303